听力与言语-语言病理学

行为科学

医学伦理学

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  • Motor cortex lesions do not affect learning or performance of the eyeblink response in rabbits.

    abstract::The possible modulatory role of motor cortex in classical conditioning of the eyeblink response was examined by ablating anterior neocortex in rabbits and training them with an auditory conditioned stimulus (CS) and an airpuff unconditioned stimulus (US) in either a delay (Experiment 1) or a trace (Experiment 2) condi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.4.727

    authors: Ivkovich D,Thompson RF

    更新日期:1997-08-01 00:00:00

  • Dissociations among the anxiolytic effects of septal, hippocampal, and amygdaloid lesions.

    abstract::Fear reactions of rats given bilateral lesions to the septum, hippocampus, or amygdala were compared with those of rats given sham lesions, in 2 animal models of anxiety: the shock-probe burying test and the elevated plus-maze test. Septal lesions produced anxiolytic effects in both tests (i.e., an increase in open-ar...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.3.653

    authors: Treit D,Menard J

    更新日期:1997-06-01 00:00:00

  • Analysis of galanin and the galanin antagonist M40 on delayed non-matching-to-position performance in rats lesioned with the cholinergic immunotoxin 192 IgG-saporin.

    abstract::Galanin is a 29-amino-acid neuropeptide that is overexpressed in Alzheimer's disease (AD) and impairs performance on rodent learning and memory tasks. M40, a peptidergic galanin receptor ligand, blocks galanin-induced impairments on delayed non-matching-to-position (DNMTP). The present experiments used the 192IgG-sapo...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.3.552

    authors: McDonald MP,Wenk GL,Crawley JN

    更新日期:1997-06-01 00:00:00

  • Sensitization of ingestive responding in preweanling rats: time course and specificity.

    abstract::Two experiments measured the response-enhancing effects of oral stimulation in young rats with no feeding experience. In Experiment 1, pups were implanted with oral cannulas and deprived for 0, 6, or 24 hr. In nondeprived rats, sucrose exposure transiently sensitized oral responding to subsequent stimuli for several m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.2.413

    authors: Myers KP,Arnold HM,Hall WG

    更新日期:1997-04-01 00:00:00

  • Identification of quantitative trait loci involved in contextual and auditory-cued fear conditioning in BXD recombinant inbred strains.

    abstract::Fear conditioning shows associations formed between contextual or auditory stimuli with an unconditioned stimulus. Inbred mouse strains differ in their ability to demonstrate fear conditioning, suggesting at least a partial genetic influence. The present study identified the possible chromosomal loci regulating fear c...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.2.292

    authors: Owen EH,Christensen SC,Paylor R,Wehner JM

    更新日期:1997-04-01 00:00:00

  • Delayed spontaneous alternation in intact and cerebellectomized control and lurcher mutant mice: differential role of cerebellar cortex and deep cerebellar nuclei.

    abstract::Lurcher mutant (+/Lc) mice exhibit a massive loss of neurons in the cerebellar cortex and in the inferior olivary nucleus while deep cerebellar nuclei are essentially intact. To discriminate the respective participation of the cerebellar cortex and deep structures in learning and memory, the authors subjected 3- to 6-...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.1.214

    authors: Caston J,Vasseur F,Delhaye-Bouchaud N,Mariani J

    更新日期:1997-02-01 00:00:00

  • Sexual behavior regulated (paced) by the female induces conditioned place preference.

    abstract::The possibility that female-paced coital behavior induces a reward state of sufficient intensity and duration to induce conditioning was evaluated by the conditioned-place-preference paradigm. Ovariectomized female rats, treated with estradiol benzoate and progesterone, regulated (paced) their coital interactions with...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.1.123

    authors: Paredes RG,Alonso A

    更新日期:1997-02-01 00:00:00

  • Correlation between head direction cell activity and spatial behavior on a radial arm maze.

    abstract::This study assessed the activity of head direction (HD) cells during performance of a spatial reference memory task on a radial arm maze. Rats were trained to select a maze arm located in a constant position in relation to a salient extramaze visual landmark. HD cell discharge properties remained relatively stable acr...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.1.3

    authors: Dudchenko PA,Taube JS

    更新日期:1997-02-01 00:00:00

  • A small amount of wheel running facilitates eating in nondeprived rats.

    abstract::A high level of dopaminergic activation such as that produced by a high dose of amphetamine suppresses eating, whereas a low level such as that produced by a low dose can have the opposite effect. Like a high dose of amphetamine, a high level of wheel running also suppresses eating. It was hypothesized that this suppr...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.6.1492

    authors: Lett BT,Grant VL,Gaborko LL

    更新日期:1996-12-01 00:00:00

  • Behavioral sensitization to cocaine, but not cocaine-conditioned behavior, is associated with increased dopamine occupation of its receptors in the nucleus accumbens.

    abstract::Rats had repeated treatments with cocaine associated with a specific context (paired group). Evidence for classical conditioning of cocaine's motor-activity effects and context-specific behavioral sensitization to cocaine was obtained, relative to vehicle-treated (control) and pseudoconditioned (unpaired) groups. Only...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.6.1388

    authors: Burechailo L,Martin-Iverson MT

    更新日期:1996-12-01 00:00:00

  • Role of the hippocampus plus subjacent cortex but not amygdala in visuomotor conditional learning in rhesus monkeys.

    abstract::Rhesus monkeys were trained to learn a large series of visuomotor conditional associations, each involving the arbitrary coupling of a visual stimulus with 1 of 3 potentially correct forelimb movements. The monkeys then received bilateral aspiration lesions of either the amygdala plus subjacent cortex or the hippocamp...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.6.1261

    authors: Murray EA,Wise SP

    更新日期:1996-12-01 00:00:00

  • Hippocampal lesions impair contextual fear conditioning in two strains of mice.

    abstract::Two different strains of mice, C57BL/6J and BALB/c, with hippocampal, cortical, or sham lesions, underwent contextual fear conditioning. In both strains, contextual fear, as measured by the freezing response, was significantly impaired in hippocampus-lesioned animals compared with sham control animals. Fear conditioni...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.5.1177

    authors: Chen C,Kim JJ,Thompson RF,Tonegawa S

    更新日期:1996-10-01 00:00:00

  • Basolateral amygdala lesions block glucocorticoid-induced modulation of memory for spatial learning.

    abstract::This study examined the role of the amygdala in mediating the effects of glucocorticoids on spatial memory in rats. Adrenalectomy (ADX) induced 4-5 days prior to training impaired memory in a water-maze spatial task. This effect was reversed by a posttraining injection of dexamethasone (0.3 mg/kg sc) but not by cortic...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.5.1074

    authors: Roozendaal B,Portillo-Marquez G,McGaugh JL

    更新日期:1996-10-01 00:00:00

  • Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine.

    abstract::The present study examined the effects of lesions of the central nucleus of the amygdala (CeA) on the acquisition of a new response with conditioned reinforcement (CR) and its potentiation by intra-accumbens infusions of d-amphetamine (1, 3, 10, and 20 microg/microl). Rats were trained to associate a light-plus-noise ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.5.981

    authors: Robledo P,Robbins TW,Everitt BJ

    更新日期:1996-10-01 00:00:00

  • Dissociable properties of memory systems: differences in the flexibility of declarative and nondeclarative knowledge.

    abstract::Amnesic patients (n = 8), who have severely impaired declarative memory, learned a probabilistic classification task at the same rate as normal subjects (n = 16) but subsequently were impaired on transfer tests that required flexible use of their task knowledge. A second group of controls (n = 20) rated the questions ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.5.861

    authors: Reber PJ,Knowlton BJ,Squire LR

    更新日期:1996-10-01 00:00:00

  • Differential behavioral response to dopamine D2 agonists by sexually naive, sexually active, and sexually inactive male rats.

    abstract::This study was performed with male rats categorized as sexually naive (SN), sexually active (SA), or sexually inactive (SI). In a first experiment the effects of dopamine (DA) D2 agonist SND 919 (0.05, 1, and 10 mg/kg) on the copulatory behavior of SN, SA and SI rats were assessed. In a second experiment the DA D2 ago...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.4.802

    authors: Giuliani D,Ferrari F

    更新日期:1996-08-01 00:00:00

  • Cognitive gender differences in very young children parallel biologically based cognitive gender differences in monkeys.

    abstract::Infant humans were trained on 2 cognitive tests that have previously revealed, in infant monkeys, a double dissociation that was reversible by perinatal manipulations of androgens and ablations of specific brain sites. Children showed the same sex-linked behavior found with infant monkeys: young boys were superior on ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.4.673

    authors: Overman WH,Bachevalier J,Schuhmann E,Ryan P

    更新日期:1996-08-01 00:00:00

  • Neonatal chorda tympani transection alters adult preference for ammonium chloride in the rat.

    abstract::The immature gustatory system of the neonatal rat is characterized by sensitivity to disruption by early interventions such as receptor or nerve damage. The present studies examined the effect of chorda tympani transection (neoCTX) of neonates on adult preference for salt and nonsalt stimuli. NeoCTX at 10 days of age ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.3.551

    authors: Sollars SI,Bernstein IL

    更新日期:1996-06-01 00:00:00

  • Cognitive impairment in rats fed high-fat diets: a specific effect of saturated fatty-acid intake.

    abstract::One-month-old rats were fed 1 of 4 high-fat diets (20% fat) or chow (4.5% fat) for 3 months. Dietary saturated (SFA), monounsaturated (MUFA), or polyunsaturated (PUFA) fatty acids varied such that their independent effects on cognitive performance could be tested. Rats were tested on a variable-interval delayed-altern...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.3.451

    authors: Greenwood CE,Winocur G

    更新日期:1996-06-01 00:00:00

  • Amygdala central nucleus lesions attenuate acoustic startle stimulus-evoked heart rate changes in rats.

    abstract::Amygdala central nucleus (CNA) lesions were used to test the hypothesis that stimulus-evoked heart rate changes can reflect the development of fear during acoustic startle testing. A 120-dB white noise startle stimulus produced freezing as well as phasic heart rate accelerations and decelerations, and an abrupt decrea...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.2.228

    authors: Young BJ,Leaton RN

    更新日期:1996-04-01 00:00:00

  • Dissociations between appetitive and consummatory responses by pharmacological manipulations of reward-relevant brain regions.

    abstract::Appetitive behaviors of rats were monitored in a runway situation following central infusions of neuroactive substances into brain areas implicated in electrical self-stimulation. Microinjections of the dopamine antagonist cis-flupentixol or the cholinergic antagonist atropine into the nucleus accumbens (Acb) severely...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.2.331

    authors: Ikemoto S,Panksepp J

    更新日期:1996-04-01 00:00:00

  • Anterior rhinal cortex and amygdala: dissociation of their contributions to memory and food preference in rhesus monkeys.

    abstract::Rhesus monkeys were trained on 2 versions of delayed nonmatching-to-sample, one with multiple pairs of objects and the other with a single pair, to evaluate their ability to remember objects. They then received either bilateral aspiration lesions of the anterior rhinal cortex or bilateral excitotoxic lesions of the am...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Murray EA,Gaffan EA,Flint RW Jr

    更新日期:1996-02-01 00:00:00

  • HemiParkinson analogue rats display active support in good limbs versus passive support in bad limbs on a skilled reaching task of variable height.

    abstract::Rats with unilateral dopamine (DA) depletion (hemiParkinson analogue rats) are impaired in using the contralateral (bad) limbs for skilled movements and for postural adjustments and compensate by using their good limbs in novel ways. The present study consisted of a reaching task in which compensatory adjustments usin...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.1.117

    authors: Miklyaeva EI,Whishaw IQ

    更新日期:1996-02-01 00:00:00

  • Overt orienting in the rat: parametric studies of cued detection of visual targets.

    abstract::Covert shifts of visual attention in space have been quantified by measuring the effects of visual cues on the detection of visual targets in humans and monkeys maintaining visual fixation. These observations of "covert orienting" have provided important information regarding the neurobiology of visual attention in pr...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.6.1095

    authors: Bushnell PJ

    更新日期:1995-12-01 00:00:00

  • Stimulus-elicited behavior in rapid eye movement sleep without atonia.

    abstract::Alert wakefulness (W) and rapid eye movement sleep (REM) are remarkably similar on several measures of brain activity, but 2 differences in REM are reduced sensory responsiveness and atonia in postural muscles. Pontine tegmental lesions create REM without atonia (REM-A), releasing motor behavior. In 9 cats, we studied...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.5.972

    authors: Morrison AR,Sanford LD,Ball WA,Mann GL,Ross RJ

    更新日期:1995-10-01 00:00:00

  • Spatial learning and memory as a function of age in the dog.

    abstract::Spatial learning and memory were studied in dogs of varying ages and sources. Compared to young dogs, a significantly higher proportion of aged dogs could not acquire a spatial delayed nonmatching-to-sample task. A regression analysis revealed a significant age effect during acquisition. Spatial memory was studied by ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.5.851

    authors: Head E,Mehta R,Hartley J,Kameka M,Cummings BJ,Cotman CW,Ruehl WW,Milgram NW

    更新日期:1995-10-01 00:00:00

  • Effects of exposure to stressors of varying predictability on adrenal function in rats.

    abstract::For 5 days, rats were exposed to shocks that were signalled by a light 0, 33, 66, or 100% of the time. Basal hormone levels and responses to a light-shock pair were measured daily. Greater predictability was associated with higher basal plasma corticosterone and norepinephrine levels indicative of chronic stress. Habi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.4.767

    authors: Pitman DL,Natelson BH,Ottenweller JE,McCarty R,Pritzel T,Tapp WN

    更新日期:1995-08-01 00:00:00

  • Taste-potentiated odor conditioning: impairment produced by infusion of an N-methyl-D-aspartate antagonist into basolateral amygdala.

    abstract::Two experiments examined the effects of infusing an N-methyl-D-aspartate (NMDA) receptor antagonist, d-2-amino-5-phosphonovalerate(d-APV), on taste-potentiated odor conditioning: a form of learning that is dependent on information processing in 2 sensory modalities. In Experiment 1, rats infused with d-APV were impair...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.4.663

    authors: Hatfield T,Gallagher M

    更新日期:1995-08-01 00:00:00

  • Increases in vocalization and motor reflex thresholds are influenced by the site of morphine microinjection: comparisons following administration into the periaqueductal gray, ventral medulla, and spinal subarachnoid space.

    abstract::The relative influence of morphine microinjected into the periaqueductal gray, ventral medulla (nucleus raphé magnus or nucleus reticularis gigantocellularis), or spinal subarachnoid space on the thresholds of responses organized at spinal (spinal motor reflexes, SMRs), medullary (vocalizations elicited during shock, ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.3.502

    authors: Borszcz GS

    更新日期:1995-06-01 00:00:00

  • Modification of the acoustic startle response in hearing-impaired C57BL/6J mice: prepulse augmentation and prolongation of prepulse inhibition.

    abstract::Modification of acoustic startle amplitude by a 10-ms tone prepulse (S1) was evaluated as a function of the interstimulus interval (ISI) between the onset of S1 and the onset of the startle-evoking stimulus (S2). Subjects were normal-hearing 1-month-old C57BL/6J (C57) mice and CBA/CaJ mice and 5-month-old C57 mice wit...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.3.396

    authors: Willott JF,Carlson S

    更新日期:1995-06-01 00:00:00

  • Species differences in the vasopressin-immunoreactive pathways in the bed nucleus of the stria terminalis and medial amygdaloid nucleus in prairie voles (Microtus ochrogaster) and meadow voles (Microtus pennsylvanicus).

    abstract::Vasopressin-immunoreactive (AVP-ir) cells in the bed nucleus of the stria terminalis (BST) and medial amygdaloid nucleus (MA) and their AVP-ir projections to the lateral septum were studied in monogamous prairie voles (Microtus ochrogaster) and promiscuous meadow voles (M. pennsylvanicus). A sexually dimorphic AVP-ir ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.2.305

    authors: Wang Z

    更新日期:1995-04-01 00:00:00

  • Hippocampectomy impairs the memory of recently, but not remotely, acquired trace eyeblink conditioned responses.

    abstract::New Zealand male rabbits (Oryctolagus cuniculus) were trained on a trace eyeblink conditioning paradigm using a 250-ms tone conditioned stimulus, a 100-ms airpuff unconditioned stimulus, and a 500-ms trace interval. Rabbits received bilateral hippocampal aspirations either 1 day or 1 month after learning. Controls con...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.2.195

    authors: Kim JJ,Clark RE,Thompson RF

    更新日期:1995-04-01 00:00:00

  • Preferential use of the landmark navigational system by head direction cells in rats.

    abstract::Previous studies have identified a population of cells recorded in the postsubiculum and the anterior thalamic nucleus (ATN) that discharge as a function of an animal's head direction (HD) in the horizontal plane. The present experiments monitored HD cell activity when rats were confronted with a situation in which di...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.1.49

    authors: Goodridge JP,Taube JS

    更新日期:1995-02-01 00:00:00

  • Sustained potential shifts in the toad tectum reflect prey-catching and avoidance behavior.

    abstract::Sustained potential shifts (SPS) were recorded for 10 s from the surface of the optic tectum of toads presented with live prey and moving artificial prey stimuli. On the anterior tectal surface, a negative SPS was followed by a positive wave; the converse was true for the posterior tectum. Some animals were immobilize...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.1.150

    authors: Laming PR,Ocherashvili IV,Nicol AU,Roughan JV,Laming BA

    更新日期:1995-02-01 00:00:00

  • Central administration of cocaine produces age-dependent effects on behavior in the fetal rat.

    abstract::Rat fetuses were exposed to cocaine, lidocaine, or saline on Gestational Day 20 or 21 to provide information about cocaine effects on behavior during prenatal development. Cocaine was administered into the cisterna magna of individual fetal subjects to restrict effects to the CNS. Behavioral effects of cocaine were co...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.108.6.1179

    authors: Simonik DK,Robinson SR,Smotherman WP

    更新日期:1994-12-01 00:00:00

  • Memory of rats with amygdala lesions induced 30 days after footshock-motivated escape training reflects degree of original training.

    abstract::This experiment was conducted to determine whether the amount of preoperative training influences the effects, on retention, of amygdala lesions induced 30 days after escape training. Rats received 1 or 10 footshock-motivated escape training trials; 30 days later, sham or neurotoxic amygdala lesions were induced. Resu...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.108.6.1080

    authors: Parent MB,West M,McGaugh JL

    更新日期:1994-12-01 00:00:00

  • Amiloride sensitivity in the neonatal rat.

    abstract::Amiloride-sensitive sodium channels in taste buds appear to play a key role in the response to NaCl stimulation, at least in adult rats. The researchers examined whether neonatal rats, which display an exaggerated preference for hypertonic NaCl solutions, lack functional amiloride-sensitive sodium channels. NaCl intak...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.108.5.981

    authors: Sollars SI,Bernstein IL

    更新日期:1994-10-01 00:00:00

  • Hippocampal and amygdaloid involvement in nonspatial and spatial working memory in rats: effects of delay and interference.

    abstract::Parametric manipulations of the task demand were used to examine the role of the hippocampus and amygdala in nonspatial and spatial working memory in rats. Hippocampal lesions produced an immediate and long-lasting impairment of nonspatial working memory in an operant task. The memory deficits increased as the delay i...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.108.5.866

    authors: Wan RQ,Pang K,Olton DS

    更新日期:1994-10-01 00:00:00

  • Abdominal vagotomy alters the structure of the ingestive behavior of rats ingesting liquid diets.

    abstract::A microstructural analysis of the licking behavior of the rat was used to investigate the effects of total abdominal vagotomy on ingestive behavior. Vagotomy decreased the meal size of milk and 3 concentrations of sucrose. The decrease was due to an increase in the decline in the rate of licking during the meal, sugge...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Davis JD,Smith GP,Kung TM

    更新日期:1994-08-01 00:00:00

  • Differential effects of postingestive feedback on the reward value of sucrose and lateral hypothalamic stimulation in rats.

    abstract::The effects of postingestive feedback on the value of intraoral sucrose and lateral hypothalamic (LH) stimulation were compared. Rats chose between a fixed LH stimulation train or a compound reward composed of the same stimulation train and an oral infusion of 1 M sucrose. The rats preferred the compound reward when p...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.108.3.559

    authors: Conover KL,Shizgal P

    更新日期:1994-06-01 00:00:00

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